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Spero Science at the 8th CIMES and the First Meeting of the EMBRAPII USP Network
Spero Science joined the 8th CIMES (ABIMO, FIESP) and the First Meeting of the EMBRAPII USP Network at HC-FMUSP. Why it matters for health-tech co-development.

Prof. Dr. Tiago Lazzaretti Fernandes
Sep 172 min read


Partner with Spero Science: Investment, Licensing and Collaboration in Regenerative Orthopedics
A guide for investors, venture funds, pharmaceutical and medical-device companies, hospitals and research institutions who want to work with Spero Science Innovation — what we are building, what stage each platform is at, and the ways to collaborate.

Prof. Dr. Tiago Lazzaretti Fernandes
Sep 124 min read


From the USP Bench to the Clinic: How a Brazilian Translational Biotech Builds Regenerative Therapies
What "translational" really means at Spero Science — the São Paulo ecosystem of USP, HC-FMUSP and Hospital Sírio-Libanês, the funding and innovation partners behind it, the ANVISA pathway for advanced therapies, and why Brazil is a strategic base for musculoskeletal regenerative medicine.

Prof. Dr. Tiago Lazzaretti Fernandes
Sep 125 min read


Multimodal AI for Musculoskeletal Diagnosis: Combining Imaging, Genetics and Patient Data
Why the next generation of orthopedic AI will not read images alone — how Spero Science AI integrates MRI and X-ray, genetic profiles and patient-reported outcomes to predict who will progress, who will respond to treatment and who needs surgery.

Prof. Dr. Tiago Lazzaretti Fernandes
Sep 124 min read


Cell Therapy for Knee Osteoarthritis: What the Randomized Evidence Actually Says
A plain-language reading of the 2024 meta-analysis of 25 randomized trials on mesenchymal stromal cell therapy for knee osteoarthritis, led by Spero Science's founders — what works, what is uncertain, and why GMP manufacturing and tissue engineering are the next step.

Prof. Dr. Tiago Lazzaretti Fernandes
Sep 125 min read


Cartilage Regeneration Without Surgery: How Chondroinductive Therapies Work
Why articular cartilage does not heal on its own, what "chondroinduction" means, and how an injectable chondroinductive molecule could treat osteoarthritis and focal cartilage lesions without open surgery — the science behind Spero Science's lead platform.

Prof. Dr. Tiago Lazzaretti Fernandes
Sep 126 min read
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